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Mértola (Portuguese pronunciation: [ˈmɛɾtulɐ] (listen)) is a municipality in southeastern Portuguese Alentejo near the Spanish border. In 2011, the population was 7,274, in an area of approximately 1,292.87 square kilometres (499.18 sq mi): it is the sixth-largest municipality in Portugal. Meanwhile, it is the second-lowest population centre by density with approximately 5.62 persons/1 square kilometre (0.39 sq mi) (second to the adjacent Alcoutim).

The Church of Nossa Senhora da Anunciação (Portuguese: Igreja Paroquial de Mértola/Igreja de Nossa Senhora da Assunção/Igreja de Nossa Senhora da Anunciação) is an 11th-century church and former mosque in the civil parish of Mértola in the municipality of Mértola, in the Portuguese Alentejo.

The Castle of Mértola (Portuguese: Castelo de Mértola) is a well-preserved medieval castle located in the civil parish and municipality of Mértola, in the Portuguese district of Beja.

The Ponte Velha de Mértola ("Old Bridge of Mértola"), also referred to as the Ponte Branca or Torre do Rio, is a structure located along the Guadiana River, in the civil parish of Mértola, municipality of Mértola, in the Portuguese district of Beja. Although named a bridge, the structure is the remains of a wharf and fortified port, linked to the defensive curtain of the walled city.