Santiago de Cali (Spanish pronunciation: [sanˈtjaɣo ðe ˈkali]), or Cali, is the capital of the Valle del Cauca department, and the most populous city in southwest Colombia, with an estimated 2,319,655 residents according to 2005-2020/DANE population projections. The city spans 560.3 km2 (216.3 sq mi) with 120.9 km2 (46.7 sq mi) of urban area, making Cali the second-largest city in the country by area and the third most populous.