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Fort Detrick is a United States Army Medical Command installation located in Frederick, Maryland. Historically, Fort Detrick was the center of the U.S. biological weapons program from 1943 to 1969. Since the discontinuation of that program, it has hosted most elements of the United States biological defense program.

Frederick High School (FHS) is a four-year public high school in Frederick, Maryland, Frederick County, Maryland, United States. A National Blue Ribbon School of Excellence, Frederick High is the oldest school in Frederick County, the school's diverse population reflects its surrounding dynamic community.

The Weinberg Center is a venue located in Frederick, Maryland. It holds various showings of music, theatre, films and visual art. The theatre was built as the Tivoli Theatre by the Stanley-Crandall concern and opened on December 23, 1926. It was the premiere movie theatre of Frederick for nearly fifty years but, after considerable damage suffered in a 1976 flood, closed.

Frederick Memorial Hospital is the only hospital in Frederick County, Maryland. It is located in the city of Frederick.

The Frederick Historic District is a national historic district in Frederick, Frederick County, Maryland. The district encompasses the core of the city and contains a variety of residential, commercial, ecclesiastical, and industrial buildings dating from the late 18th century to 1941. Notable are larger detached dwellings in the Queen Anne and American Foursquare architectural styles of the late 19th and early 20th centuries The churches reflect high style architecture ranging from Gothic and Greek Revival to Richardsonian Romanesque and Colonial Revival.

All Saints Church, or All Saints Episcopal Church, founded in 1742, is a historic Episcopal church now located at 106 West Church Street in the Historic District of Frederick, Maryland. It is the seat of All Saints Parish, Diocese of Maryland, which covers most of Frederick County, Maryland and once covered most of Western Maryland.

The Frederick City Police Department (FPD) is a law enforcement organization that provides police services to the city of Frederick, Maryland, the second-largest city in that state. The department is organized into several divisions, and is responsible for policing more than 68,000 people in a land area of 22.9 square miles.

The Frederick Armory is one of a series of similar armories built for the Maryland National Guard in the early 20th century. The building explicitly copies features of medieval fortifications, with crenelated blocks at either end of a buttressed drill hall.It was listed on the National Register of Historic Places in 1985.

Beth Sholom is a Conservative synagogue, currently located in Frederick, Maryland.

Congregation Kol Ami is a Reform synagogue in Frederick, Maryland, United States.