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The Mount Holyoke College Art Museum (established 1876) in South Hadley, Massachusetts, is located on the Mount Holyoke College campus and is a member of Museums10. It is one of the oldest teaching museums in the country, dedicated to providing firsthand experience with works of significant aesthetic and cultural value.

Mount Holyoke College is a private liberal arts women's college in South Hadley, Massachusetts. It is the oldest member of the historic Seven Sisters colleges, a group of elite women's colleges in the Northeastern United States.The college was founded in 1837 as the Mount Holyoke Female Seminary by Mary Lyon, a pioneer in education for women.

South Hadley ( (listen), HAD-lee) is a town in Hampshire County, Massachusetts, United States. The population was 17,514 at the 2010 census, and was estimated to be 17,791 in 2017. It is part of the Springfield, Massachusetts Metropolitan Statistical Area.South Hadley is home to Mount Holyoke College, South Hadley High School, Pioneer Valley Performing Arts Charter Public School, and the Berkshire Hills Music Academy.

The Odyssey Bookshop is an independent bookstore in South Hadley, Massachusetts. In addition to an extensive trade book selection, The Odyssey is the exclusive provider of textbooks for Mount Holyoke College and hosts author readings and book club events.

The First Congregational Church of South Hadley (also known locally as the Center Church) is a historic church building at 1 Church Street in the center of South Hadley, Massachusetts. Completed in 1895, it is a prominent local example of Richardsonian Romanesque architecture, designed by Henry J. Preston.

The Mount Holyoke College Botanic Garden, in South Hadley, Massachusetts, United States, encompasses the Mount Holyoke College campus, an arboretum, numerous gardens, and the Talcott Greenhouse. It was first designated a botanical garden in 1878, with guidance from Lydia Shattuck, professor of botany.

The US Post Office—South Hadley Main is a historic post office at 1 Hadley Street in South Hadley, Massachusetts. Built in 1940 as part of a federal government jobs program, it is a prominent local example of simplified Classical Revival architecture. The building was listed on the National Register of Historic Places in 1986.