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Madisonville is a city in Madison County, Texas, United States. The population was 4,396 at the 2010 census. It is the county seat of Madison County. Both the City of Madisonville and the County of Madison were named for U.S. President James Madison, the fourth chief executive.

The Madison County Courthouse is the courthouse in Madisonville, Texas.The current structure was built in 1969. It is at least the fifth courthouse to serve Madison County.In 2013, it was listed in "Five Of The Ugliest Texas County Courthouses" by Houstonia magazine.

The Shapira Hotel, at 209 N. Madison St. in Madisonville, Texas was built in 1904. It was listed on the National Register of Historic Places in 1980.It has elements of Queen Anne architecture. It has also been known as Wills Hotel.