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Portlaoise Prison (Irish: Príosún Phort Laoise) is a maximum security prison in Portlaoise, County Laois, Ireland. Until 1929 it was called the Maryborough Gaol. It should not be confused with the Midlands Prison, which is a newer, medium security prison directly beside it.The prison was built in the 1830s, making it one of the oldest still operating today in the Irish prison system.

The Midlands Regional Hospital, Portlaoise (Irish: Ospidéal Réigiúnach Lár Tíre, Port Laoise) is a public hospital located in Portlaoise, County Laois, Ireland. It is managed by Dublin Midlands Hospital Group.

St. Fintan's Hospital (Irish: Ospidéal Naomh Fintan) is a psychiatric hospital in Port Laoise, County Laois, Ireland.

Laois County Infirmary (Irish: Otharlann Chontae Laoise) was a hospital in Port Laoise, County Laois, Ireland.