It saddens me to say this,but I have Rheumatoid arthritis in my entire body joints and internally. yes even your connective tissue and organs can be effective. Anyway,its been super hot and humid in the mitten state so I've been using the treadmill. this cause pain in the top of one foot and cause it to swell pretty bad so I had to take three rest days and elevate the foot. I hope to be back at it on Monday.